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Variability in the shapes of satellite cells in normal and injured frog sartorius muscle
Authors:Rosemary Mazanet  Barbara F Reese  Clara Franzini-Armstrong  Thomas S Reese
Institution:1. Department of Anatomy (G3), University of Pennsylvania, Philadelphia, Pennsylvania 19104 USA;2. Department Biology (G7), University of Pennsylvania, Philadelphia, Pennsylvania 19104 USA;2. Laboratory of Neuroanatomical Sciences, National Institute of Communicative Diseases and Stroke, NIH, Bethesda, Maryland 20205, USA;4. the Marine Biological Laboratory, Woods Hole, Massachusetts 02543 USA
Abstract:Surface topography of satellite cells is examined in the scanning electron microscope after application of a new method to eliminate connective tissue components. We describe the overall shape of satellite cells in normal frog muscle and show the range of variation in normal structure. Small increases in the width of tails and changes in the cell outline occur after muscle injury in vivo and after incubation in vitro. These changes may be signs of early mobilization of satellite cells related to their eventual role in muscle regeneration.
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