Hibiscus acid as an inhibitor of starch digestion in the Caco-2 cell model system. |
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| Authors: | C Hansawasdi J Kawabata T Kasai |
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| Institution: | Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Sapporo, Japan. |
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| Abstract: | Hibiscus acid, an alpha-amylase inhibitor isolated from roselle tea, and its derivatives were compared in an inhibition test for starch digestion. An alpha-amylase-added Caco-2 system was established as a useful model to evaluate the effects of alpha-glucosidase inhibitors on starch digestion. Hibiscus acid showed weak inhibition in this model system, and the methyl ester derivatives showed even weaker or no acitivity. |
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