Manganese inhibits benzoyl peroxide/copper-dependent lipid peroxidation in the microsomal fraction of rabbit dental pulp |
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| Authors: | Y Tsujimoto K Nagashima T Kawashima H Takeuchi M Chiba A Hashimoto T Miyoshi T Takase Y Kikuchi M Yamazaki |
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| Institution: | Department of Endodontics, Nihon University School of Dentistry at Matsudo, Japan. |
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| Abstract: | 1. Of all the cations tested only manganese ion inhibited the benzoyl peroxide/Cu2+-dependent formation of thiobarbituric acid (TBA)-reactive substance. 2. Ki of Mn2+ for the formation of TBA-reactive substance was 5.0 microM. 3. The inhibitory manner of manganese was non competitive against copper. |
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