The new numerology of immunity mediated by virus-specific CD8(+) T cells |
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Authors: | Doherty P C |
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Affiliation: | Department of Immunology, St Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA. peter.doherty@stjude.org |
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Abstract: | Our understanding of virus-specific CD8(+) T cell responses is currently being revolutionized by peptide-based assay systems that allow flow cytometric analysis of effector and memory cytotoxic T lymphocyte populations. These techniques are, for the first time, putting the analysis of T-cell-mediated immunity on a quantitative basis. |
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