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Assembly of recently translated full-length and C-terminal truncated human gamma-globin chains with a pool of alpha-globin chains to form Hb F in a cell-free system
Authors:Adachi Kazuhiko  Zhao Yi  Lakka Vinaysagar  Weiss Mitchell J  Surrey Saul
Institution:The Children's Hospital of Philadelphia, Division of Hematology, University of Pennsylvania School of Medicine, 34th Street & Civic Center Boulevard, Philadelphia, PA 19104, USA. adachi@email.chop.edu
Abstract:
Keywords:Hemoglobin  Fetal hemoglobin  Hemoglobin γ-chain  Hemoglobin α-chain  Protein assembly  Polysome profile  Nascent protein  Cell-free system  AHSP (α-globin stabilizing protein)  Hemoglobinopathies
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