Properties of recombination-deficient mutants of bacteriophage lambda |
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| Authors: | M J Shulman L M Hallick H Echols E R Signer |
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| Affiliation: | 2. SynthSys - Centre for Synthetic and Systems Biology, University of Edinburgh, UK;1. University of Split, Faculty of Civil Engineering, Architecture and Geodesy, Matice hrvatske 15, Split, HR-21000, Croatia;2. Institute of Earthquake Engineering and Engineering Seismology (IZIIS), University of Ss. Cyril and Methodius, Todor Aleksandrov 165, Skopje, MK-1000, Republic of Macedonia;1. Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan;2. Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan 710, Taiwan;3. Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung 40402, Taiwan;4. Department of Biological Science & Technology, I-Shou University, Kaohsiung City 84001, Taiwan;5. Department of Chemical Engineering, Feng Chia University, 100 Wenhwa Road, Taichung 40724, Taiwan;6. Department of Health and Nutrition Biotechnology, Asia University, Taichung 41354, Taiwan;1. Department of Biology, Duke University, Durham, NC 27708, USA;2. University Program in Genetics and Genomics, Duke University, Durham, NC 27708, USA;3. Center for Genomics and Computational Biology, Duke University, Durham, NC 27708, USA |
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| Abstract: | We have studied the complementation behavior, genetic mapping and exonuclease activity of various recombination-deficient (red−) mutants of bacteriophage λ. In collaboration with C. Radding (Radding, 1970), we have observed that the red− mutants tested often affect one or both of two gene products—exonuclease and β-protein—indicating that these proteins are involved in genetic recombination. |
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