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Hybridization of nickel oxide nanoparticles with carbon dots and its application for antibacterial activities
Authors:Dugasa Jabesa Nemera  Habtamu Fekadu Etefa  Vinod Kumar  Francis Birhanu Dejene
Institution:1. Department of Chemistry, College of Natural Sciences, Jimma University, Jimma, Ethiopia;2. Department of Physics, College of Natural and Computational Science, Dambi Dollo University, Ethiopia;3. Department of Chemical and Physical Sciences, Walter Sisulu University, Private Bag X1, Mthatha, South Africa
Abstract:A nickel oxide nanoparticle (NiO NP) composite with carbon dots (C-dots), (NiO NPs@C-dots) was synthesized, characterized, and then its antibacterial activity was evaluated. NiO NPs were prepared using Buddleja polystachya Fresen leaf extract and Ni(NO3)2.6H2O as precursors. The C-dots were synthesized from benzene-1,4-diamine and citric acid. The cubic structure of the NiO NPs and NiO NPs@C-dots was in phase with their average particle size distributions of 21.47 ± 0.56 and 21.61 ± 0.34 nm, respectively. The surface morphology of the NiO NPs@C-dots was characterized using field emission scanning electron microscopy and also revealed a large surface area, which is advantageous for the specified application. The X-ray diffraction result indicated a cubic face wurtzite structure and the crystalline nature of the NiO NPs. Carbon-doped compounds had no influence on the crystal structure of the NiO compound and no new peaks were observed. The antibacterial activity of a composite made up of NiO NPs@C-dots was tested, as well as the antibacterial activities of compounds produced against human photogenic bacterial strains. Both NiO NPs and NiO NPs@C-dots were found to be powerful against all bacterial strains, based on the bioassay results. NiO NPs and NiO@C-dots appeared to display strong to inhibitory effects of 14–20 mm and 17–23 mm, respectively.
Keywords:C-dots  DMSO and antibacterial activities  Gentamycin  NiO  NiO@C-dots
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