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Tspan6 stimulates the chemoattractive potential of breast cancer cells for B cells in an EV- and LXR-dependent manner
Institution:1. Institute of Cancer and Genomic Sciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK;2. Department of Clinical and Molecular Pathology, Palacky Univerzity, 7779 00 Olomouc, Czech Republic;3. Institute of Immunology and Immunotherapy, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK;4. Aston Medical Research Institute, Aston Medical School, Aston University, Birmingham B4 7ET, UK;5. Department of Pathology, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt;6. Faculty of Medicine, Institute for Infection Prevention and Hospital Epidemiology, Medical Center - University of Freiburg, 79106 Freiburg, Germany;7. Leeds Institute of Medical Research, University of Leeds, St James’s University Hospital, Leeds LS9 7TF, UK;8. Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK;9. German Cancer Consortium (DKTK), Partner Site Freiburg and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany;10. Translational Cancer Research Unit Center for Oncological Research, University Antwerp, Antwerp 2610, Belgium
Abstract:
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  • Keywords:B cells  breast cancer  tumor microenvironment  tetraspanins  oxysterols  LXR  CP: Cancer
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