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A human T-cell antigen receptor beta chain gene maps to chromosome 7. |
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| Authors: | M K Collins P N Goodfellow M J Dunne N K Spurr E Solomon and M J Owen |
| Abstract: | cDNA clones which encode the human and mouse T cell antigen receptor beta chain gene have previously been isolated. We have used a mouse cDNA clone to map the chromosomal position of a human beta chain gene. Southern blot analysis of DNA prepared from somatic cell hybrids has assigned this gene to chromosome 7. The use of a hybrid containing a chromosome 7 translocation has further localised this gene to the region 7q22-qter. |
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