New triterpenoidal alkaloids from Buxus sempervirens |
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Authors: | Ata Athar Naz Samina Choudhary M Iqbal Atta-ur-Rahman Sener Bilge Turkoz Songul |
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Affiliation: | Department of Chemistry, The University of Winnipeg, Manitoba, Canada. chemistry@c-h.uwinnipeg.ca |
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Abstract: | Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16a, 31-diacetylbuxadine (1), (-)-Nb-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3), (-)-cyclobuxophylline-K (4) and (+)-buxaquamarine (5) isolated for the first time from this species of genus Buxus. The structures of these new natural products were established on the basis of extensive spectroscopic studies. Compound 1 exhibited antibacterial activity against human pathogenic bacteria and weak phytotoxic activity against Lemna minor Linn. |
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