Chronotype and Body Composition in Bipolar Disorder |
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| Authors: | Isabella Soreca Andrea Fagiolini Ellen Frank Bret H Goodpaster David J Kupfer |
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| Institution: | 1. Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USAsorecai@upmc.edu;3. Department of Psychiatry, University of Siena School of Medicine, SienaItaly;4. Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA;5. Department of Endocrinology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA |
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| Abstract: | We explored whether obesity in patients with bipolar disorder is associated with their chronotype. A group of 29 patients with bipolar I disorder, not currently experiencing an affective episode, were assessed for total body fat, mood symptoms, and self-reported circadian chronotype and sleep quality. Chronotype explained 19% of the variance in body fat, after age, sex, mood state, and sleep quality were accounted for. This association suggested that evening chronotype patients have a higher percentage of total body fat. Evening chronotype could be a proxy for as yet unknown specific causes of the high rate of obesity and obesity-related diseases in bipolar disorder. |
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| Keywords: | Bipolar disorder Chronotype Body composition |
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