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The pathogenicities of Cylindrocarpon tonkinense and Fusarium solani in the rabbit cornea |
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| Authors: | Yasuhisa Ishibashi Herbert E Kaufman Tadahiko Matsumoto Saburo Kagawa |
| Institution: | (1) LSU Eye Center, Louisiana State University Medical Center School of Medicine, 70112 New Orleans, LA, USA;(2) Present address: Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, J-305 Ibaraki, Japan;(3) Department of Dermatology, Faculty of Medicine, Kyushu University, J-812-60 Fukuoka, Japan;(4) Department of Dermatology, Tokyo Medical & Dental University School of Medicine, J-113 Tokyo, Japan |
| Abstract: | The pathogenicity of Cylindrocarpon tonkinense in the cornea was evaluated and compared with that of Fusarium solani in rabbits. F. solani was inoculated into the right eyes of 14 rabbits and C. tonkinense was into the left eyes of same rabbits. The corneal lesions of both eyes were examined carefully by slit lamp every day for three weeks and the severity of infections were compared each other. For histopathologic study, several eyes were enucleated periodically. C. tonkinense has a pathogenicity equally strong as F. solani in this inculum size (104 microconidia per cornea) and produced severe infection in rabbit eyes. |
| Keywords: | pathogenicity Cylindrocarpon tonkinense Fusarium solani experimental fungal keratitis cornea rabbit |
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