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Genomic research for important pathogenic bacteria in China
Authors:RuiFu Yang  XiaoKui Guo  Jian Yang  YongQiang Jiang  Bo Pang  Chen Chen  YuFeng Yao  JinHong Qin  QingTian Li
Affiliation:1. Laboratory of Analytical Microbiology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China
2. Department of Medical Microbiology and Parasitology, Institutes of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
3. State Key Laboratory for Molecular Virology and Genetic engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences, Beijing, 100176, China
4. State Key Laboratory for Infectious Disease Prevention and Control, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China
5. Beijing Genomics Institute at Shenzhen, Shenzhen, 518083, China
Abstract:Rapid accumulation of bacterial genomic data offered an unprecedented opportunity to understand bacterial biology from a holistic view of point.We can thus closely look at the way in which a pathogen is evolved,and these data has been applied to molecular epidemiology and microbial forensics,and screening of novel diagnostic,vaccine and drug targets.The newly developed high-throughput low-cost sequencing technologies,such as 454,Solexa and SOLiD,will promote the acquisition and application of genomic data i...
Keywords:genome  pathogenic bacteria  sequencing  application  
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