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Antioxidant features of fungal melanin pigments
Authors:Shcherba V V  Babitskaia V G  Kurchenko V P  Ikonnikova N V  Kukulianskaia T A
Affiliation:Institute of Microbiology, Belarussian Academy of Sciences, Minsk, Belarus.
Abstract:Fungal melanin pigments were shown to display a high antioxidant activity. An increase in the number of methyl substituents in benzidine molecules of melanins obtained from micromycetes and macromycetes was accompanied by a decrease in the efficiency of inhibition of peroxidase-catalyzed oxidation. Melanins were found to have considerable gene-protecting properties. Pigments isolated from macromycetes and applied at a much lower concentration than those obtained from micromycetes prevented damage to bacteriophage-lambda DNA induced by products of peroxidase-catalyzed degradation of aminobiphenyls.
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