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A Matrix Protein Silences Transposons and Repeats through Interaction with Retinoblastoma-Associated Proteins
Authors:Yifeng Xu  Yizhong Wang  Hume Stroud  Xiaofeng Gu  Bo Sun  Eng-Seng Gan  Kian-Hong Ng  Steven E Jacobsen  Yuehui He  Toshiro Ito
Institution:1. Temasek Life Sciences Laboratory (TLL), 1 Research Link, National University of Singapore, Singapore 117604, Singapore;2. Department of Biological Sciences, Faculty of Science, National University of Singapore, 10 Science Drive 4, 117543, Singapore;3. Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA;4. Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA
Abstract:
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  • Highlights? The Arabidopsis matrix protein TEK silences transposons and repeat-containing genes ? Binding of TEK on targets affects chromatin conformation and histone modifications ? TEK protein associates with FVE/MSI5-containing histone deacetylation complex ? TEK directs repressive modification as a key structural component in gene silencing
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