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Selective Chemical Crosslinking Reveals a Cep57-Cep63-Cep152 Centrosomal Complex
Authors:Gra?vydas Lukinavi?ius  Darja Lavogina  Meritxell Orpinell  Keitaro Umezawa  Luc Reymond  Nathalie Garin  Pierre Gönczy  Kai Johnsson
Institution:1. Institute of Chemical Sciences and Engineering (ISIC), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne 1015, Switzerland;2. School of Life Sciences, Swiss Institute for Experimental Cancer Research (ISREC), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne 1015, Switzerland;3. Leica Microsystems AG, Heerbrugg 9435, Switzerland
Abstract:
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  • Highlights? Selective chemical crosslinking identifies novel protein-protein interactions ? Superresolution microcopy defines the localization of centrosomal proteins ? Cep57, Cep63, and Cep152 form a ring-like centrosomal complex
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