1. Institute for Research in Biomedicine (IRB Barcelona), Carrer de Baldiri Reixac 10-12, 08028 Barcelona, Spain;2. Institució Catalana de Recerca i Estudis Avançats (ICREA);3. Institute of Evolutionary Biology (CSIC-UPF), Passeig Marítim de la Barceloneta 37-49, 08003 Barcelona, Spain
Abstract:
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Highlights? bantam is required in ecdysone-producing cells to promote body growth ? bantam inhibits ecdysone biosynthesis ? Insulin signaling regulates ecdysone production by repressing bantam activity ? Both the systemic and tissue-autonomous activities of bantam promote organ growth
