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Discovery of diarylurea P2Y1 antagonists with improved aqueous solubility |
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| Authors: | Tammy C. Wang Jennifer X. Qiao Charles G. Clark Ji Jua Laura A. Price Qimin Wu Ming Chang Joanna Zheng Christine S. Huang Gerry Everlof William A. Schumacher Pancras C. Wong Dietmar A. Seiffert Anne B. Stewart Jeffrey S. Bostwick Earl J. Crain Carol A. Watson Robert Rehfuss Patrick Y.S. Lam |
| Affiliation: | Medicinal Chemistry, Molecular Sciences and Candidate Optimization, Bristol-Myers Squibb, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA |
| Abstract: | |
| Keywords: | Diarylurea Structure–activity relationship (SAR) Aqueous solubility In vivo efficacy/bleeding model |
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