1. Developmental and Stem Cell Biology Department, Institut Pasteur, 75015 Paris, France;2. CNRS, URA2578, 75015 Paris, France
Abstract:
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Highlights? Numb relocalizes from the cortex to sorting endosomes at cytokinesis ? Numb is not essential for the internalization of Notch and Sanpodo ? Numb inhibits the recycling of Notch and Sanpodo ? Recycling inhibition in one daughter cell imposes directionality to Notch signaling