Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB

Authors:	Nazim Ali Ling Zhang Sandra Taylor Alex Mironov Sylvie Urbé Philip Woodman

Institution:	1. Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK;2. Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK

Abstract:	Download : Download high-res image (201KB) Download : Download full-size image Highlights? HD-PTP is essential for sorting EGFR to the MVB lumen ? HD-PTP binds the ESCRT-0 subunit STAM2 at two sites ? CHMP4B and UBPY displace EGFR from ESCRT-0 and drive ESCRT-III association ? UBPY is important for sorting EGFR to the MVB lumen

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