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Gle1 does double duty
Authors:Kutay Ulrike  Panse Vikram Govind
Institution:Institute of Biochemistry, ETH Zurich, Schafmattstrasse 18, CH-8093 Zürich, Switzerland. ulrike.kutay@bc.biol.ethz.ch
Abstract:During nuclear export, Gle1 (the nuclear-pore-associated mRNA export factor) activates the DEAD-box protein Dbp5 to remodel exported mRNA-protein complexes on the cytoplasmic face of the nuclear pore complex. In this issue, Bolger et al. (2008) now report additional roles for Gle1 in translation initiation and termination.
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