Silencing HIV-1 In Vivo |
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| Authors: | Kirchhoff Frank |
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| Affiliation: | Institute of Virology, University of Ulm, 89081 Ulm, Germany. frank.kirchhoff@uniklinik-ulm.de |
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| Abstract: | RNA interference holds great promise for antiviral therapy, but delivering effective quantities of small interfering RNAs (siRNAs) into the right target cells in vivo represents a major challenge. Kumar et al. (2008) now report a technique to target siRNAs specifically to T cells to suppress viral infection in a humanized mouse model of HIV/AIDS. |
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