Triterpenoid saponins from Mollugo spergula. |
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| Authors: | N P Sahu K Koike S Banerjee B Achari T Nikaido |
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| Affiliation: | Indian Institute of Chemical Biology, 4 Raja S C Mullick Road, Calcutta 700032, India. npsahu@iicb.res.in |
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| Abstract: | Two novel triterpenoid saponins belonging to a modified hopane group, spergulin A [3-O-(beta-D-xylopyranosyl 4-sulphate)-spergulagenin A] (1) and spergulin B [3-O-[alpha-rhamnopyranosyl (1-->2)-beta-D-xylopyranosyl]-spergulatriol] (4) were isolated from the aerial part of Mollugo spergula along with spergulacin (2) and spergulacin A (3). Their structures and relative stereochemistry were determined by a combination of 2D-NMR (COSY, TOCSY, HETCOR, NOESY and HMBC) and HR-FAB-MS analysis coupled with strategic chemical and enzymatic transformations. |
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