Temperature difference between the body core and arterial blood supplied to the brain during hyperthermia or hypothermia in humans |
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Authors: | Maithreyi Bommadevara Liang Zhu |
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Institution: | (1) Department of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA e-mail: zliang@umbc.edu Fax: +1-410-4551052, US |
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Abstract: | A vascular heat transfer model is developed to simulate temperature decay along the carotid arteries in humans, and thus,
to evaluate temperature differences between the body core and arterial blood supplied to the brain. Included are several factors,
including the local blood perfusion rate, blood vessel bifurcation in the neck, and blood vessel pairs on both sides of the
neck. The potential for cooling blood in the carotid artery by countercurrent heat exchange with the jugular veins and by
radial heat conduction to the neck surface was estimated. Cooling along the common and internal carotid arteries was calculated
to be up to 0.87 °C during hyperthermia by high environmental temperatures or muscular exercise. This model was also used
to evaluate the feasibility of lowering the brain temperature effectively by placing ice pads on the neck and head surface
or by wearing cooling garments during hypothermia treatment for brain injury or other medical conditions. It was found that
a 1.1 °C temperature drop along the carotid arteries is possible when the neck surface is cooled to 0 °C. Thus, the body core
temperature may not be a good indication of the brain temperature during hyperthermia or hypothermia.
Received: 10 January 2002 / Accepted: 7 May 2002
This research was supported by a UMBC Summer Faculty Fellowship. |
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