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Regulation of Foxo-1 and the angiopoietin-2/Tie2 system by shear stress
Authors:Chlench Sven  Mecha Disassa Nigussie  Hohberg Margret  Hoffmann Christian  Pohlkamp Theresa  Beyer Gabriele  Bongrazio Mauro  Da Silva-Azevedo Luis  Baum Oliver  Pries Axel Radlach  Zakrzewicz Andreas
Affiliation:Charité, Campus Benjamin Franklin, Institute of Physiology, Arnimallee 22, 14195 Berlin, Germany.
Abstract:
Keywords:Akt, RAC-alpha serine/threonine-protein kinase   Ang-1, angiopoietin-1   Ang-2, angiopoietin-2   eNOS, endothelial NO-synthase   Foxo-1, Forkhead box protein O1A   HUVEC, human umbilical vein endothelial cells   Kip, cyclin-dependent kinase inhibitor p27   PI3K, phosphatidyl inositol 3 kinase   Tie2, tyrosine-protein kinase receptor   VEGF, vascular endothelial growth factor
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