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Excitatory neuromuscular transmission in crayfish: Calcium dependence is unaffected by picrotoxin |
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| Authors: | D. R. Staggs E. Pofcher Ramona L'Heureux C. L. Ortiz R. K. Orkand |
| Abstract: | Picrotoxin, 1 × 10?5M to 1.6 × 10?3M, had little or no effect on the amplitude of intracellularly recorded excitatory junctional potentials (EJPs) at extracellular calcium concentrations [Ca2+]0 ranging from 0.5 to 15 mM. The slope of the log EJP vs. log[Ca2+]0 relationship was approximately 1 with or without picrotoxin. The reduction of EJP amplitude resulting from the addition of 5 × 10?5M GABA was largely reversed by 10?5M picrotoxin. |
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