潍坊市坊子区2012年产前HBsAg筛检及新生儿首针乙肝疫苗接种情况分析

目的：了解住院分娩产妇乙肝病毒表面抗原（ HBsAg）检测及其所生新生儿首针乙肝疫苗及时接种情况，为进一步完善新生儿乙型肝炎的免疫预防策略提供依据。方法对2012年坊子区设有产科的医院每月上报的产妇HBsAg 检测和新生儿首针乙肝疫苗接种资料进行分析。结果坊子区2012年设有产科的医疗机构共报告住院分娩产妇2975名，产前HBsAg筛检2881名，筛检率为96．84％，各医疗机构筛检率在96．55％和97．50％之间；检出HBsAg阳性者66例，阳性率为2．29％，各医疗机构阳性率在0．00％和5．52％之间。新生儿共2975名，其中常住者所生新生儿2612名，流动者所生新生儿363名，常住和流动的新生儿乙肝疫苗接种率分别为96．13％和94．21％，及时接种率分别为93．87％和90．36％，差异均无统计学意义（χ2＝2．98、3．67，P＞0．05）。122名未及时接种首针乙肝疫苗的新生儿系患各种疾病所致。结论坊子区2012年设有产科的医院对住院的孕产妇产前HBsAg筛查率较高，其所生的新生儿24 h内乙肝疫苗及时接种率较高。

Analysis on maternal HBsAg screening and newborn first dose of hepatitis B vaccination of Fangzi district of Weifang city in 2012

Objective To understand HBsAg screening in pregnant women and the inoculation of first dose of human hepa -titis B vaccine in their newborns , so as to provide the basis for the further improvement of immune prevention strategies a-gainst neonatal hepatitis B infection .Methods To collect and analyze the data about HBsAg screening among pregnant women and first dose of hepatitis B vaccination for their newborns , which were reported to local center for disease control and prevention by the hospitals in every month .Results About 2 975 woman who were delivered newborns were reported from the departments of obstetrics of medical institutions in Fangzi in 2012 .2 881 pregnant women had been done the sur-veillance for pre-natal HBsAg , and surveillance rate is 96.84%, the rate was in between 96.55%and 97.50%in differ-ent medical organizations.66 cases are HBsAg positive, the positive rate is 2.29%the rate was in between 0 and 5.52%in different medical organizations .Among 2 975 newborns , 2 612 are residential newborns , 363 are migrant newborns .the coverage rates for HB vaccine inoculation are 96.13% and 94.21% in resident and migrant newborns , respectively, the timely vaccination coverage rates are 93.87% and 90.36%,respectively, the difference does not have statistical signifi-cance （χ2=2.98, 3.67, P〉0.05）.In 122 newborns who were not inoculated the first dose of HB vaccine , some of them failed to timely vaccination for suffered illness and so on .Conclusion HBsAg screening rate in pregnant women was high-er among those who were delivered newborns in hospitals , the timely dose coverage rate of HB vaccine for their newborns was also higher in Fangzi district .