PI3K enters beta-testing |
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| Authors: | Shaywitz Adam J Courtney Kevin D Patnaik Akash Cantley Lewis C |
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| Affiliation: | Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. |
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| Abstract: | Phosphoinositide-3-OH kinases (PI3K) are critical regulators of cell metabolism, growth, and survival. In a recent publication in Nature, Jia et al. (2008) identify specific functions of the p110beta isoform of PI3K in glucose metabolism, cellular proliferation, and tumorigenesis. |
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