Genome analysis of DNA repair genes in the alpha proteobacterium Caulobacter crescentus |
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Authors: | Marinalva Martins-Pinheiro Regina CP Marques Carlos FM Menck |
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Affiliation: | (1) Department of Microbiology, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes 1374, 05508-900 So Paulo, SP, Brazil |
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Abstract: | Background The integrity of DNA molecules is fundamental for maintaining life. The DNA repair proteins protect organisms against genetic damage, by removal of DNA lesions or helping to tolerate them. DNA repair genes are best known from the gamma-proteobacterium Escherichia coli, which is the most understood bacterial model. However, genome sequencing raises questions regarding uniformity and ubiquity of these DNA repair genes and pathways, reinforcing the need for identifying genes and proteins, which may respond to DNA damage in other bacteria. |
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