Bioactive constituents from roots of Bursera tonkinensis |
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| Authors: | Jutiviboonsuk Aranya Zhang Hongjie Tan Ghee Teng Ma Cuiying Van Hung Nguyen Manh Cuong Nguyen Bunyapraphatsara Nuntavan Soejarto D Doel Fong Harry H S |
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| Institution: | Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447 Si Ayutthaya Road, Ratchathewi District, Bangkok 10400, Thailand. |
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| Abstract: | Bioassay directed-fractionation led to isolation of 12 compounds from the roots of Bursera tonkinensis Guillaum (Burseraceae), including burselignan, bursephenylpropane, and burseneolignan. Of the 12 compounds, only 4'-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lines. |
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| Keywords: | Bursera tonkinensis Burseraceae Cytotoxicity Burselignan Burseneolignan Bursephenylpropane |
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