Selective vasodilatation effect of sargahydroquinoic acid, an active constituent of Sargassum micracanthum, on the basilar arteries of rabbits |
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| Authors: | Park Byong-Gon Shin Woon-Seob Um Yumi Cho Sungsik Park Gab-Man Yeon Dong-Soo Kwon Seong-Chun Ham Jungyeob Choi Byoung Wook Lee Seokjoon |
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| Institution: | College of Medicine, Kwandong University, Gangneung, Gangwon 210-701, Republic of Korea. |
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| Abstract: | Sargahydroquinoic acid (2), a major active constituent of Sargassum micracanthum collected from the coast of the East Sea in Korea, showed a selective vasodilatation effect on the basilar arteries of rabbits. Therefore, treatment with sargahydroquinoic acid may selectively accelerate cerebral blood flow through dilatation of the basilar artery without lowering systemic blood pressure. |
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