Morphological and chromosomal characterization of three new continuous cell lines of Drosophila melanogaster |
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Authors: | Giuliana Mosna Silvana Dolfini |
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Institution: | (1) Institute of Genetics, University of Milano, Italy |
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Abstract: | Three continuous cell lines (GM1, GM2 and GM3) were obtained from embryos of Drosophila melanogaster. Karyotypic analysis revealed characteristics distinguishing each line. Except for some minor variations GM1 cells had an X and a centric heterochromatic fragment (which is a portion of the Y). GM2 line was characterized by XO cells showing two new telocentric chromosomes while an autosome of the II pair was missing. GM3 cells were XY; the Y chromosome, however, was shorter than the normal, having a deletion of the terminal section of the short arm. Several problems concerning the origin of these different genomes are discussed.This work was supported by a grant of the Consiglio Nazionale delle Ricerche, Roma. |
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