Serotypes and mating types of clinical strains ofCryptococcus neoformans isolated in Taiwan |
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Authors: | Mark Ming-Long Hsu MD Jen-Chyi Chang Koji Yokoyama Kazuko Nishimura Makoto Miyaji |
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Affiliation: | (1) Department of Dermatology, National Cheng-Kung University Medical Center, Tainan, Taiwan;(2) Department of Medical Technology, National Cheng-Kung University Medical Center, Tainan, Taiwan;(3) Research Centre for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Inohana, Chiba, Japan;(4) Department of Dermatology, National Cheng-Kung University Hospital, 138 Sheng-Li Road, Tainan, Taiwan |
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Abstract: | Twenty-one strains ofCryptococcus neoformans isolated from patients in Taiwan were characterized for serotypes and mating types. Slide agglutination test was performed with 8 factor-specific sera (Iatron Company, Japan) to determine the serotypes. Wheat bran agar (WBA) and malt extract agar (MEA, Wickerham) media were used for the mating tests. Twenty of the isolates were of serotype A, and one was serotype B. Except for 2 strains of serotype A, all of the serotype A strains mated withFilobasidiella neoformans var.neoformans, mating type a. The only serotype B strain mated withF. neoformans var.bacillispora mating type a in MEA medium. These data revealed the low prevalence (1/21; 4.8%) ofC. neoformans var.gattii in Taiwan, a subtropically located island. |
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Keywords: | Cryptococcus neoformans Mating type Serotype |
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