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PIANA: protein interactions and network analysis
Authors:Aragues Ramon  Jaeggi Daniel  Oliva Baldo
Affiliation:Structural Bioinformatics Group (GRIB-IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Doctor Aiguader, 83, Barcelona 08003, Catalonia, Spain. ramon.aragues@upf.edu
Abstract:We present a software framework and tool called Protein Interactions And Network Analysis (PIANA) that facilitates working with protein interaction networks by (1) integrating data from multiple sources, (2) providing a library that handles graph-related tasks and (3) automating the analysis of protein-protein interaction networks. PIANA can also be used as a stand-alone application to create protein interaction networks and perform tasks such as predicting protein interactions and helping to identify spots in a 2D electrophoresis gel. Availability: PIANA is under the GNU GPL. Source code, database and detailed documentation may be freely downloaded from http://sbi.imim.es/piana.
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