Blastomycosis in Africa |
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| Authors: | William F Carman John A Frean Heather H Crewe-Brown Gary A Culligan Celia N Young |
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| Institution: | (1) Department of Microbiology, School of Pathology of the South African Institute for Medical Research and the University of the Witwatersrand, P O Box 1038, 2000 Johannesburg, South Africa;(2) Department of Microbiology, Medical University of Southern Africa, Medunsa, South Africa;(3) Department of Microbiology, Medical University of Southern Africa, Medunsa, South Africa;(4) Mycology Laboratory, Department of Microbiology, School of Pathology of the South African Institute for Medical Research and the University of the Witwatersrand, South Africa;(5) Present address: Department of Medicine, St. Mary's Hospital Medical School, W2 INY Paddington London;(6) Present address: Wellcome (Pty) Ltd, Kempton Park, South Africa |
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| Abstract: | The known African cases of blastomycosis to 1987 are presented, including thirteen previously undescribed cases. This brings to 81 the total number of cases known to have occurred in Africa. The question of whether the disease in Africa is the same in all respects as that in North America is addressed; the age and sex distributions of patients are similar. Minor differences in the clinical features relate particularly to the type of skin lesion, the more frequent bone involvement and the less frequent central nervous system involvement in the African patient. Little is known about the epidemiology of blastomycosis in Africa; one noteworthy feature is the apparent absence of the disease in dogs. Isolates of Blastomyces dermatitidis from the two continents, although closely related, differ in some respects. |
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| Keywords: | Blastomyces dermatitidis Africa North America clinical features epidemiology |
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