Probable congenital transmission of reticuloendotheliosis virus caused by vaccination with contaminated vaccines |
| |
| Authors: | Kai Wei Zhenhong Sun Shufen Zhu Wenlong Guo Pengcheng Sheng Zunmin Wang Changliang Zhao Qingyou Zhao Ruiliang Zhu |
| |
| Affiliation: | Key Laboratory of Biological Product, College of Animal Science and Technology, Shandong Agricultural University, Taian, Shandong, People's Republic of China. |
| |
| Abstract: | Contaminated vaccine is one unexpected and potential origin of virus infection. In order to investigate the most likely cause of disease in a broiler breeder company of Shandong Province, all 17 batches of live-virus vaccines used in the affected flocks and 478 tissue samples were tested by dot-blot hybridization, nested PCR, and IFA. The results suggested the outbreak of disease was most probably due to the vaccination of REV-contaminated MD-CVI988/Rispens vaccines and ND-LaSota+IB-H120 vaccines. Furthermore, the REV was probably transmitted to the commercial chickens through congenital transmission. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
