| 细胞不对称分裂 |
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| 引用本文： | 潘正军 陈忠科. 细胞不对称分裂[J]. 细胞生物学杂志, 2005, 27(6): 613-616 |
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| 作者姓名： | 潘正军 陈忠科 |
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| 作者单位： | 山东大学生命科学学院发育生物学研究所,济南250100 |
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| 摘 要： | 细胞不对称分裂是多细胞生物发育的基础。细胞不对称分裂的重要特征是细胞命运决定子在细胞分裂期间的不对称分离。细胞不对称分裂一般要经历4个步骤：在细胞中建立一个极性轴；沿此轴定向并形成纺锤体；细胞命运决定子沿极性轴作极性分布；细胞分裂后，不同的细胞命运决定子指导决定细胞的不同命运。
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| 关 键 词： | 细胞不对称分裂 极性轴 细胞命运决定子 |
| 收稿时间： | 2005-04-11 |
| 修稿时间： | 2005-06-16 |
Asymmetric Cell Division |
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| Zheng-Jun Pan, Zhong-Ke Chen. Asymmetric Cell Division[J]. Chinese Journal of Cell Biology, 2005, 27(6): 613-616 |
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| Authors: | Zheng-Jun Pan Zhong-Ke Chen |
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| Affiliation: | Institute of Developmental Biology, School of Life Science, Shandong University, Jinan 250100, China |
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| Abstract: | Asymmetric cell division is the foundation of multicellular organism development. The charac- teristics of asymmetric cell division are asymmetric segregation of cell fate determinants into one of the two daugh- ter cells. Asymmetric cell division proceeds through four steps: first, an axis of polarity is established. Second, the mitotic spindle is set up and oriented along this axis of polarity. Third, cell fate determinants are distributed in a polarized fashion along this axis. Fourth, different concentrations of these determinants in the two daughter cells lead to the establishment of distinct cell fates after cell division. |
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| Keywords: | asymmetric cell division axis of polarity cell fate determinant |
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