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Metformin synergizes 5-fluorouracil,epirubicin, and cyclophosphamide (FEC) combination therapy through impairing intracellular ATP production and DNA repair in breast cancer stem cells |
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| Authors: | Jaslyn Sian-Siu Soo Char-Hong Ng Si Hoey Tan Rozita Abdul Malik Yew-Ching Teh Boon-Shing Tan Gwo-Fuang Ho Mee-Hoong See Nur Aishah Mohd Taib Cheng-Har Yip Felicia Fei-Lei Chung Ling-Wei Hii Soo-Hwang Teo Chee-Onn Leong |
| Affiliation: | 1. Cancer Research Initiatives Foundation, Sime Darby Medical Centre, 1 Jalan SS12/1A, 47500, Subang Jaya, Selangor, Malaysia 2. Department of Surgery, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia 3. Breast Cancer Research Unit, Faculty of Medicine, University Malaya Medical Centre, University Malaya Cancer Research Institute, University of Malaya, 50603, Kuala Lumpur, Malaysia 4. Center for Cancer and Stem Cell Research, International Medical University, 126 Jalan 19/155B, 57000, Bukit Jalil, Kuala Lumpur, Malaysia 6. Department of Clinical Oncology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia 5. Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan |
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