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Replication-competent adenoviruses with the type 35-derived fiber-knob region achieve reactive oxygen species-dependent cytotoxicity and produce greater toxicity than those with the type 5-derived region in pancreatic carcinoma |
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| Authors: | Suguru Yamauchi Kiyoko Kawamura Shinya Okamoto Takao Morinaga Yuanyuan Jiang Masato Shingyoji Ikuo Sekine Shuji Kubo Yuji Tada Koichiro Tatsumi Hideaki Shimada Kenzo Hiroshima Masatoshi Tagawa |
| Affiliation: | 1. Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, 666-2 Nitona, Chuo-ku, Chiba, 260-8717, Japan 2. Department of Molecular Biology and Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan 3. Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan 4. Division of Respirology, Chiba Cancer Center, Chiba, Japan 5. Department of Genetics, Hyogo College of Medicine, Nishinomiya, Japan 6. Department of Surgery, School of Medicine, Toho University, Tokyo, Japan 7. Department of Pathology, Tokyo Women’s Medical University Yachiyo Medical Center, Yachiyo, Japan |
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