The effect of ionizing radiation on the functional properties of hemoglobin from fractionated cells of dog bone marrow

Cell populations of dog bone marrow enriched by erythroid cells were obtained by fractionation in a sucrose density gradient. Functional properties of the haemoglobin isolated from nucleate erythrocyte precursors were studied during the radiation injury development. The haemoglobin of later nucleate forms of the erythroid series of irradiated dog bone marrow exhibited an increase in its affinity to oxygen.