| 细菌群体感应信号分子——酰基高丝氨酸内酯的检测 |
| |
| 引用本文： | 宋水山,黄媛媛. 细菌群体感应信号分子——酰基高丝氨酸内酯的检测[J]. 细胞生物学杂志, 2007, 29(5): 697-700 |
| |
| 作者姓名： | 宋水山 黄媛媛 |
| |
| 作者单位： | 河北省生物研究所 石家庄050051 |
| |
| 基金项目： | 国家自然科学基金;河北省自然科学基金 |
| |
| 摘 要： | 革兰氏阴性菌根据信号分子N-酰基高丝氨酸内酯(AHLs)的浓度可以监测周围环境中自身或其他细菌的数量变化,当信号分子达到一定浓度阈值时,能启动相关基因的表达来适应环境的变化,这一调控系统被称为细菌的群体感应(quorumsensing,QS)系统。快速简便而有效地检测细菌是否以及产生何种信号分子成为深入研究和了解细菌群体感应的重要手段。现对信号分子AHLs敏感的用于检测不同的信号分子AHLs的微生物传感菌进行综述,并对其检测能力进行了讨论。
|
| 关 键 词： | N-酰基高丝氨酸内酯 细菌的群体感应系统 微生物传感菌 信号分子 |
| 修稿时间： | 2007-03-02 |
Detection of Quorum Sensing N-acylhomoserine lactones Signal Molecules |
| |
| Shui-Shan Song,Yuan-Yuan Huang. Detection of Quorum Sensing N-acylhomoserine lactones Signal Molecules[J]. Chinese Journal of Cell Biology, 2007, 29(5): 697-700 |
| |
| Authors: | Shui-Shan Song Yuan-Yuan Huang |
| |
| Affiliation: | Biology Institute of Hebei, Shijiazhuang 050051, China |
| |
| Abstract: | Many Gram-negative bacteria use N-acylhomoserine lactones (AHLs) as quorum sensing (QS) signal molecules to communicate with each other, synchronize related gene expression and response collectively to a changing environment. Bacterial quorum sensing plays essential roles in controlling and coordinating a variety of bacterial behavior. Simple and effective protocols for detecting and analyzing various signal molecules are of importance for identifying and understanding bacterial quorum sensing. The present article introduces and discusses the currently available microbial sensor strains used in detecting different kinds of AHLs. |
| |
| Keywords: | N-acylhomoserine lactones bacterial quorum sensing microbial sensor signal molecules |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
