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Edgotype: a fundamental link between genotype and phenotype
Affiliation:1. Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;2. Department of Genetics, Harvard Medical School, Boston, MA 02115, USA;1. Donnelly Centre and Departments of Molecular Genetics and Computer Science, University of Toronto, Toronto, Ontario M5S 3E1, Canada;2. Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Ontario M5G 1X5, Canada;3. Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA;1. Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette, cedex, France;2. Sorbonne Universités, UPMC Univ Paris 06, UFR927, F-75005, Paris, France;3. CNRS, Université de Paris, UPR 9080, Laboratoire de Biochimie Théorique, 13 Rue Pierre et Marie Curie, F-75005, Paris, France;4. Institut de Biologie Physico-Chimique-Fondation Edmond de Rothschild, PSL Research University, Paris, France;1. Department of Biology, Norwegian University of Science and Technology (NTNU), Trondheim, Norway;2. Department of Computer Science and Engineering, Instituto Superior Técnico (IST) – Universidade de Lisboa, Lisbon, Portugal;3. INESC-ID, Lisbon, Portugal;4. Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway;5. The Cancer Clinic, St. Olav’s Hospital, Trondheim, Norway;1. Program in Systems Biology and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA;2. Department of Cancer Biology, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA 02215, USA;3. Department of Genetics, Harvard Medical School, Boston, MA 02115, USA;1. Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA;2. Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA;3. Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94158, USA;4. Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA;5. Department of Bioinformatics & Computational Medicine, University of Michigan, Ann Arbor, MI 48109, USA;6. Donnelly Centre and Departments of Molecular Genetics and Computer Science, University of Toronto, Toronto, ON M5S 3E1, Canada;7. Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON M5G 1X5, Canada;8. Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;9. Canadian Institute for Advanced Research, Toronto, ON M5G 1Z8, Canada;10. Department of Electrical Engineering, University of Washington, Seattle, WA 98195, USA;11. Department of Computer Science & Engineering, University of Washington, Seattle, WA 98195, USA;12. Howard Hughes Medical Institute, Seattle, WA 98195, USA;13. Department of Bioengineering, University of Washington, Seattle, WA 98195, USA;1. Section of Genetic Medicine, Department of Medicine, University of Chicago, IL, USA;2. Institute for Genomics and Systems Biology, University of Chicago, Chicago, IL, USA;3. Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women''s Hospital, Boston, MA, USA;4. Harvard Medical School, Boston, MA, USA;5. Program in Medical and Population Genetics, The Broad Institute, Cambridge, MA, USA
Abstract:
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