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Comparative genomics approaches to understanding and manipulating plant metabolism
Institution:1. School of Life Science and Biotechnology, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200240, China;2. SJTU-Yale Joint Center for Biostatistics, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200240, China;3. Department of Biostatistics, Yale University, New Heaven, USA
Abstract:
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  • Highlights? Comparative genomics can help predict the function of unknown plant metabolic genes. ? Functional gene annotations are foundational to the construction of metabolic models. ? Models can simulate effects of genetic changes and thus guide metabolic engineering. ? Examples of comparative genomics facilitating gene discovery in plants are presented.
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