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Cobalt derivatives as promising therapeutic agents
Affiliation:1. Faculty of Chemistry, University of Gdansk (Gdańsk), Wita Stwosza 63, 80-308 Gdansk (Gdańsk), Poland;2. Institute of Chemistry, Jan Kochanowski University, Świętokrzyska (Swietokrzyska) 15 G, 25-406 Kielce, Poland;1. Institute of Inorganic Chemistry, Slovak University of Technology, Bratislava SK-81237, Slovakia;2. Department of Chemistry (FPV), University of SS Cyril and Methodius, 91701 Trnava, Slovakia;1. Department of Inorganic and Physical Chemistry, Indian Institute of Science, Sir C.V. Raman Avenue, Bangalore 560012, India;2. Department of Molecular Reproduction and Development Genetics, Indian Institute of Science, Sir C.V. Raman Avenue, Bangalore 560012, India;1. Department of Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic;2. Department of Chemical and Geological Sciences, University of Cagliari, Monserrato (CA), Italy;3. Department of Histology and Embryology, Faculty of Medicine, Masaryk University, Brno, Czech Republic;4. Department of Chemistry, Faculty of Science, University of La Laguna, La Laguna, Tenerife, Spain;1. Department of In Vitro Carcinogenesis and Cellular Chemotherapy, Chittaranjan National Cancer Institute, 37, S.P. Mukherjee Road, Kolkata 700 026, India;2. Department of Pharmacology, Institute of Post Graduate Medical Education and Research, 244, A.J.C. Bose Road, Kolkata 700020, India;3. Centre for Research in Nanoscience and Nanotechnology, University of Calcutta, India;1. Surface Engineering & Tribology Group, CSIR-Central Mechanical Engineering Research Institute, Mahatma Gandhi Avenue, Durgapur 713209, West Bengal, India;2. Academy of Scientific & Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi 110001, India;3. Vidyasagar College for Women, 39 Sankar Ghosh Lane, Kolkata 6, West Bengal, India;4. CSIR-Central Glass and Ceramic Research Institute (CGCRI), Kolkata, West Bengal, India
Abstract:
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  • Highlights► Cobalt is a versatile transition metal for drug development. ► The tunable physicochemical properties can be exploited by understanding the mechanism of bioactive cobalt complexes. ► The review highlights examples of mechanistic investigations of cobalt therapeutics.
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