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Synthesis and cytotoxicity of aurilide analogs |
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| Authors: | Suenaga Kiyotake Kajiwara Shuri Kuribayashi Satomi Handa Tomohisa Kigoshi Hideo |
| Affiliation: | aDepartment of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku, Yokohama 223-8522, Japan;bDepartment of Chemistry, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8571, Japan |
| Abstract: | The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure–activity relationships were investigated. |
| Keywords: | Aurilide Cytotoxicity Structure– activity relationships Cyclodepsipeptide |
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