| 链霉菌真核型丝氨酸/苏氨酸蛋白激酶的研究进展 |
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| 引用本文： | 杨旭,关东明,王胜兰等.链霉菌真核型丝氨酸/苏氨酸蛋白激酶的研究进展[J].微生物学报,2008,48(1):126-131. |
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| 作者姓名： | 杨旭 关东明 王胜兰等 |
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| 作者单位： | 1. 中国矿业大学化学与环境工程学院,北京,100083
2. 中国科学院微生物研究所,北京,100101 |
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| 摘 要： | 简要回顾了丝/苏氨酸蛋白激酶在链霉菌中的发现过程,详细介绍了链霉菌中几个研究较为深入的丝/苏氨酸蛋白激酶的功能,同时对天蓝色链霉菌Streptomyces coelicolor A3(2)和除虫霉菌Streptomyces avermitilis MA-4680中的丝/苏氨酸蛋白激酶的跨膜种类和蛋白结构域特点作了初步的生物信息学分析.
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| 关 键 词： | 丝氨酸/苏氨酸蛋白激酶 链霉菌 结构域 调节 天蓝色链霉菌 核型 丝氨酸 苏氨酸蛋白激酶 研究进展 Streptomyces update Review 生物信息学分析 结构域 种类 跨膜 avermitilis 虫霉菌 功能 发现过程 |
| 文章编号： | 0001-6209（2008）01-0126-06 |
| 收稿时间： | 2007-04-06 |
| 修稿时间： | 2007-07-06 |
An update of Streptomyces eukaryotic-type Ser/Thr protein kinases--A Review |
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| Xu Yang,Dongming Guan and Shenglan Wang.An update of Streptomyces eukaryotic-type Ser/Thr protein kinases--A Review[J].Acta Microbiologica Sinica,2008,48(1):126-131. |
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| Authors: | Xu Yang Dongming Guan and Shenglan Wang |
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| Institution: | China University of Mining and Technology, School of Chemical and Environmental Engineering;China University of Mining and Technology, School of Chemical and Environmental Engineering;China University of Mining and Technology, School of Chemical and Environmental Engineering |
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| Abstract: | We review briefly the strategies and processes to identify Ser/Thr protein kinases from Streptomycesspp. and discussed in detail the functions of well studied Ser/Thr protein kinases, such as AfsK. We used bioinformatic methods to predict transmembrane regions in Ser/Thr protein kinases of S. coelicolor A3(2) and S. avermitilis. The complete sets of Ser/Thr protein kinases from genomes of Streptomyces coelicolor A3(2) and Streptomyces avermitilis MA-4680 were categorized based on domain analyses. |
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| Keywords: | Ser/Thr protein kinases Streptomyces domain regulation |
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