Effect of prostaglandin F2α on endocrine-ovarian function in the domestic cat |
| |
Authors: | DE Wildt WB Panko SWJ Seager |
| |
Institution: | Institute of Comparative Medicine, Baylor College of Medicine Texas Medical Center, Houston, Texas 77030 U.S.A. |
| |
Abstract: | The effect of prostaglandin F2α(PGF2α) on endocrine and ovarian function during the early luteal phase of the domestic cat was investigated. Queens were induced to ovulate and then injected subcutaneously with 0.5–5.0 mg PGF2α/kg body weight. The greatest dose was found to approach toxicity. Concentrations of progesterone were similar in cats following treatment with PGF2α compared to values of controls. Development and regression of corpora lutea as determined by serial laparoscopy were similar in all groups. These data indicate that PGF2α at the tested dosages, given during the early luteal phase is not luteolytic in this species and suggest that these regimens would be ineffective for the premature termination of pseudopregnancy. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |