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Acyl sulfonamide anti-proliferatives. Part 2: activity of heterocyclic sulfonamide derivatives
Authors:Mader Mary M  Shih Chuan  Considine Eileen  Dios Alfonso De  Grossman Cora Sue  Hipskind Philip A  Lin Ho-Shen  Lobb Karen L  Lopez Beatriz  Lopez José E  Cabrejas Luisa M Martin  Richett Michael E  White Wesley T  Cheung Yiu-Yin  Huang Zhongping  Reilly John E  Dinn Sean R
Institution:Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA. mader_mary@lilly.com
Abstract:The anti-proliferative activity of acylated heterocyclic sulfonamides is described in Vascular Endothelial Growth Factor-dependent Human Umbilical Vascular Endothelial Cells (VEGF-HUVEC) and in HCT116 tumor cells in a soft agar diffusion assay.
Keywords:
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