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p53 suppresses hyper-recombination by modulating BRCA1 function
Institution:1. Department of Environment and Health, School of public health, Shandong University, Jinan, Shandong Province 250012, China;2. The Second Hospital of Shandong University, Jinan, Shandong Province 250033, China;3. Department of Radiation Oncology and Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States;1. Institute of Experimental Medicine, Pavlova str., 12, St., Petersburg 197376, Russia;2. ITMO University, Kronverksky av., 49, St., Petersburg 197101, Russia;3. Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya str., 29, St., Petersburg 195251, Russia;4. School of Liberal Arts and Sciences, Mercy College of Health Sciences, Des Moines, IA, USA;1. Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan;2. Department of Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan;1. Graduate Program in Immunology, Sackler School of Biomedical Sciences, Tufts University Boston, MA 02111, USA;2. Medical Scientist Training Program, Tufts University School of Medicine, Boston, MA 02111, USA;3. Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA;1. Department of Neurology, Cedars-Sinai Medical Center, Los Angeles 90048, USA;2. McKinsey & Company, Beijing, China;3. Department of Surgery, Division of Trauma and Critical Care, Cedars-Sinai Medical Center, Los Angeles 90048, USA;1. Department of Neurosurgery, Tufts Medical Center and Tuft University School of Medicine, 800 Washington Street, Boston, MA 02111, USA;2. Department of Anatomic Pathology, Lahey Clinic, Burlington, MA, USA;3. Department of Neurosurgery, Lahey Clinic, Burlington, MA, USA;1. Department of Pathology, Hospital Universitario Central de Asturias, Oviedo, Spain;4. Unit of Dermatopathology, Hospital Universitario Central de Asturias, Oviedo, Spain;5. Service of Dermatology II, Hospital Universitario Central de Asturias, Oviedo, Spain;6. Department of Otolaryngology, Instituto Universitario de Oncología del Principado de Asturias, Hospital Universitario Central de Asturias, Oviedo, Spain;2. Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, New Hampshire;3. Universidad Autónoma de Chile, Santiago, Chile
Abstract:
Keywords:p53  BRCA1  Hyper-recombination  Chromosomal stability  Homologous recombination
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