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Cell cycle-regulated promoters in budding yeast
Authors:L Breeden
Affiliation:1. Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, ON M5G 1L7, Canada;2. Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, ON M5G 1L7, Canada;3. McEwen Center for Regenerative Medicine, University Health Network, Toronto, ON M5G 1L7, Canada;4. Dr. John T. Macdonald Foundation Department of Human Genetics and John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA;5. Swinburne University of Technology, Sarawak Campus, Kuching 93350, Sarawak, Malaysia;6. Centre for Personalised Cancer Medicine, University of Adelaide, Adelaide SA 5000, Australia;7. Department of Molecular Genetics, University of Toronto, Toronto, ON M5G 1X5, Canada;8. Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1X5, Canada;9. Department of Physiology, University of Toronto, Toronto, ON M5G 1X5, Canada;1. Department of Physiology, Northwestern University Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA;2. Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA;3. Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia;4. The School of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072 Australia;5. Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia;6. Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia;7. Robinson Research Institute, School of Medicine, University of Adelaide, Adelaide, SA 5005, Australia;1. Department of Biochemistry, Faculty of Pharmacy, Heliopolis University, 3 Cairo-Belbeis Desert Road, P.O. Box 3020 El Salam, 11785 Cairo, Egypt;2. Department of Biochemistry and Molecular Biology, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City, Cairo 11823, Egypt;3. Department of Pharmacology and Toxicology, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City, Cairo 11884, Egypt;4. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Heliopolis University, 3 Cairo-Belbeis Desert Road, P.O. Box 3020 El Salam, 11785 Cairo, Egypt;5. Department of Biochemistry and Molecular Biology, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City, Cairo 11823, Egypt;6. Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt;7. Department of Biochemistry, Faculty of Pharmacy and Drug Technology, Egyptian Chinese University, Cairo 11786, Egypt;1. Department of Human Genetics, Radboudumc, Nijmegen, The Netherlands;2. Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands;3. Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands;4. Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen, The Netherlands;5. Department of Clinical Genetics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom;6. Clinical Genetics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom;7. Advocate Children''s Hospital, Park Ridge, IL;8. Genetic Laboratory of Rare and Autoinflammatory Diseases, Department of Medical Genetics, Rare Diseases and Personalized Medicine, Centre Hospitalier Universitaire de Montpellier, Montpellier, France;9. Service de Génétique, Hospices Civils de Lyon, Bron, France;10. Institut NeuroMyoGene, CNRS UMR5310, INSERM U1217, Université Claude Bernard Lyon 1, Lyon, France;11. Génétique des Anomalies du Développement, Université de Bourgogne Franche-Comté, UMR1231-Inserm, Dijon, France;12. Laboratoire de Génétique Chromosomique et Moléculaire, UF6254 Innovation en Diagnostic Génomique des Maladies Rares, Centre Hospitalier Universitaire de Dijon, Dijon, France;13. Department of Neurology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY;14. Service de Génétique Moléculaire et Génomique Médicale, CHU de Rennes, Rennes, France;15. University of Rennes, CNRS, IGDR, UMR 6290, Rennes, France;16. South West Thames Regional Clinical Genetics Service, St George''s Hospital, University of London, London, United Kingdom;17. GeneDx, Gaithersburg, MD;18. Centre de Génétique et Centre de Référence Anomalies du Développement et Syndromes Malformatifs de l''Interrégion Est, Centre Hospitalier Universitaire Dijon, Dijon, France;19. Fédération Hospitalo-Universitaire Médecine Translationnelle et Anomalies du Développement (TRANSLAD), Centre Hospitalier Universitaire Dijon, Dijon, France;20. Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indiana University, Indianapolis, IN;21. Medical Genetic Department, Rare Diseases and Personalized Medicine, Montpellier University, Inserm U1183, CHU Montpellier, Montpellier, France;22. Department of Plastic and Reconstructive Surgery and Hand Surgery, Dutch Craniofacial Center, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands;23. Department of Bioinformatics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands;24. Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN;25. Oxford Centre for Genomic Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom;26. Department of Clinical and Molecular Genetics, Vall d''Hebron University Hospital and Medicine Genetics Group, Vall d''Hebron Research Institute, Barcelona, Spain;27. Department of Clinical Genetics, Children''s Health Ireland at Crumlin and Temple Street, Dublin, Ireland;28. West of Scotland Centre for Genomic Medicine, Queen Elizabeth University Hospital, Scottish Genomes Partnership, Glasgow, United Kingdom;29. CHU Rennes, Service de Génétique Clinique, Centre de Référence Maladies Rares CLAD-Ouest, ERN ITHACA, Hôpital Sud, Rennes, France;30. Service de Génétique - Centre de Référence Anomalies du Développement, Hospices Civils de Lyon, Bron, France;31. Équipe GENDEV, Centre de Recherche en Neurosciences de Lyon, INSERM U1028 CNRS UMR5292, Université Claude Bernard Lyon 1, Lyon, France;32. Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands;33. Department of Clinical Genetics, Maastricht University Medical Center+, Maastricht University, Maastricht, The Netherlands;34. Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN;35. Department of Clinical Genetics, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom;36. Center of Excellence for Neuropsychiatry, Vincent van Gogh Institute for Psychiatry, Venray, The Netherlands
Abstract:Cell cycle-regulated promoters are activated in response to specific cues in the cell cycle. By studying the mechanism of their transient activation, we may identify the molecules that trigger progress through the cell cycle.
Keywords:
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